Ultrasonic Study of Methyl Cobalamine Drug At 35 0c & 45 0c

Abstract

In the present study ultrasonic velocity (U), density (ρ) and viscosity (η) have been measured at frequency 1 MHz in the binary mixtures of methyl cobalamine with water in the concentration range (0.1 to 0.0125 %) at 35 0C & 45 0C using Multifrequency ultrasonic interferometer. The measured value of density, ultrasonic velocity, and viscosity have been used to estimate the acoustical parameters namely adiabatic compressibility (βa), relaxation time (τ), acoustic impedance (z), free length (Lf), free volume (Vf) and internal pressure (ᴨ), Wada’s constant to investigate the nature and strength of molecular interaction in the binary mixture of methyl cobalamine with water. The obtained result support the complex formation, molecular association by intermolecular hydrogen bonding in the binary liquid mixtures.